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RTC-Emul
Intelligent Vacuum Emulsification System Module

Module Overview

The Vacuum Emulsification Process Module achieves efficient mixing and stable emulsification of oil and water phases through vacuum deaeration, high-shear homogenization, and precise temperature control, producing uniform and stable emulsions or creams. The system enables fully closed production from pre-mixing, homogenization, deaeration, to filling, compliant with GMP, ISO 22716, and FDA 21 CFR Part 211 standards, ideal for sterile or high-active-ingredient formulations.

Core Components

Key Process Control Points

Vacuum Deaeration & Foam Control

● Precise vacuum adjustment (-0.08~-0.1 MPa), ≥95% deaeration efficiency, eliminating bubbles to prevent oxidation or filling defects

● Online foam sensors linked to vacuum pumps for dynamic defoaming

High-Shear Homogenization

● Multi-stage homogenizer control (rotor-stator design, 1000–10000 rpm adjustable), D90 particle size ≤5μm (nanoemulsions: 100–500 nm)

● Real-time shear energy monitoring (torque sensors) to prevent localized overheating and ingredient degradation (e.g., pharmaceutical creams)

Precision Temperature Control

● Jacketed emulsification vessel (double/triple layers), PID temperature control (±0.5°C), rapid heating/cooling (oil melting + water phase dissolution), thermal fluid/ice-water circulation for high-viscosity materials (e.g., high-wax-content creams)

Emulsion Stability Control

● Online viscometer+ conductivity meter to monitor phase transition, auto-adjust stirring speed and homogenization intensity

● Closed-loop pH control (acid/alkali auto-dosing) for formulation stability (e.g., personal care products pH 5.5–6.5)

Cleaning & Sterility Assurance

● Full CIP/SIP system (acid/alkali cleaning + pure steam sterilization), dead-leg residue ≤0.1%

● 316L stainless steel, Ra ≤0.4μm mirror finish, compliant with 3D-ASTM E2700 cleanliness standards (pharmaceutical grade)

Data Traceability & Compliance

● Automated electronic batch records with critical parameters (vacuum level, homogenization time, temperature curves)

● Role-based access + audit trails aligned with EU GMP Annex 11 data integrity requirements

Industry Applications

Cosmetics

Creams, lotions, sunscreens

Personal Care

Shampoos, serums, body washes

Pharmaceuticals

Topical ointments, nanoemulsions, softgel capsules

Fine Chemicals

Specialty lubricants, electronic coating materials

Core Advantages

High Efficiency & Energy Savings

Vacuum deaeration reduces emulsification time by 40%; heat recovery cuts energy use by 25%

Flexible Configuration

Modular design with expandable homogenization units

Safety & Compliance

ATEX explosion-proof certification (solvent-based formulations), sterile-grade design (pharmaceutical ointments)

Service Support

Process Validation Package

Emulsification trials and validation documentation

Customized Solutions

Explosion-proof (chemical), sterile (pharmaceutical), lab-scale pilot machines (R&D)

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